Hepatic Function Panel
Component Reference Range Date - 3/18/13 Date 8/9/13
AST (SGOT) 13-40 U/L 64 34
ALT (SGPT) 7-52 U/L 121 47
AST (SGOT)
AST, or aspartate aminotransferase, is 1 of the 2 "liver enzymes." It is also known as serum glutamic-oxaloacetic transaminase, or SGOT. AST is a protein made by liver cells. When liver cells are damaged, AST leaks out into the bloodstream and the level of AST in the blood becomes higher than normal. AST is different from ALT because AST is found in parts of the body other than the liver--including the heart, kidneys, muscles, and brain. When cells in any of those parts of the body are damaged, AST can be elevated.
Explanation of test results:
A high AST level often means there is some liver damage, but it is not necessarily caused by hepatitis C. A high AST with a normal ALT may mean that the AST is coming from a different part of the body. It is important to realize that the AST level in most patients with hepatitis C goes up and down. The exact AST level does not tell you how much liver damage there is, or whether the liver is getting better or worse, and small changes should be expected. However, for patients receiving treatment for hepatitis C, it is helpful to see if the AST level goes down.
ALT (SGPT)
ALT, or alanine aminotransferase, is 1 of the 2 "liver enzymes." It is sometimes known as serum glutamic-pyruvic transaminase, or SGPT. It is a protein made only by liver cells. When liver cells are damaged, ALT leaks out into the bloodstream and the level of ALT in the blood is higher than normal.
Explanation of test results:
A high ALT level often means there is some liver damage, but it may not be related to hepatitis C. It is important to realize the ALT level goes up and down in most patients with hepatitis C. The ALT level does not tell you exactly how much liver damage there is, and small changes should be expected. Changes in the ALT level do not mean the liver is doing any better or any worse. The ALT level does not tell you how much scarring (fibrosis) is in the liver and it does not predict how much liver damage will develop.
http://www.hepatitis.va.gov/patient/diagnosis/labtests-ALT.asp
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